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arterial blood and venous blood model

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Sulfonylureas (glyburide, glipizide, glimepiride) and meglitinides (nateglinide, repaglinide) increase insulin secretion via closure of ATP-dependent K+ channels on the pancreatic beta cell... overdose of these can cause HYPOGLYCEMIA... these are the only oral hypoglycemic agents for DM2 that cause hypoglycemia in overdose

Sulfonylureas (glyburide, glipizide, glimepiride) and meglitinides (nateglinide, repaglinide) increase insulin secretion via closure of ATP-dependent K+ channels on the pancreatic beta cell. overdose of these can cause HYPOGLYCEMIA.