Longevity Letter

I can't believe how many months I procrastinated in writing this blog post. Among deadlines and diaper changes, it just took me that much time to put my thoughts in order regarding a part of aging that I thought was crystal clear: aging leads to slow clearance therefore autophagy induction must always be a good thing. Wrong!

Veroudering is een puzzel die opgelost kan worden. Welke mechanismen staan aan de basis van deze ongelijkheid in veroudering tussen soorten? Ik heb er opzettelijk voor gekozen het antwoord op deze vraag in eenvoudige taal te formuleren. Onderzoek naar veroudering is te belangrijk om te verhullen met formeel wetenschappelijk jargon. Dit boek zou niet hebben bestaan zonder de uitvinding van groene thee, bibliotheken en het internet. De hoeveelheid data die ik heb doorgespit om de essentiële…

Like all aging species, humans get worse at dealing with stress as time goes by. When dealing with stress, humans differ not only by age but also by kind. Being one of the few people who can't deal w

There are several clinical trials worldwide targeting fibrosis in diverse pathologies, most of them age-related diseases. Unfortunately, many times the endpoint in such trials is a certain organ

Through their systemic effects, pharmacological adaptogens may trigger in a shorter time what evolution is capable of after lots of generations: an increased level of stress resistance at advanced ages and with it delayed aging and longer lifespans. As such, this group of substances could provide a different strategy to slow the rate of aging and postpone the onset of many age-related diseases.

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#restrição calórica com #nutrição ótima #longevidade #envelhecimento #gerontologia #ciência #dieta #perda de peso #livros #biologia #senescência

#kalorie #beperking met optimale #voeding #langslewendheid #veroudering #gerontologie #dieet #gewig verloor #wetenskap #Nutrisie #persoonlike #gesondheid #nie-fiksie #boeke #e-boeke #Afrikaans

I read about the evolutionary theory of aging years ago and I immediately shelved it since I didn't have any idea on how it could be used to solve aging in humans. It didn't occur to me that you cou

After spending the last years of my life pondering on aging and working with people at the end of their lives, I welcomed the challenge of turning one fertilized egg into an adult. This marathon is

I was curious whether this shark could share any molecular tricks for its extreme lifespan, but research on it is quite scarce. Its size and extreme environment are understandable deterrents from

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Lessons from human embryo development and other species

Rome wasn't built in a day and neither is longevity attained overnight. A few years ago I read about the compound effect: it's this idea that baby steps done regularly lead to extraordinary

While extreme longevity and negligible senescence are generally the domain of plants and colonial animals, bivalves as a group rock the boat when it comes to long-lived non-colonial animals. Of course