Most people strum with their right hand and hold the neck with their left. It’s really similar to a guitar or bass – just super tiny. It’s great for ladies for that reason. You don’t need calluses to play the ukulele like you do with a guitar. Also, you don’t need a guitar pick. Standard Tuning is G C E A. That means your top string is tuned to G. Then C. Then E. A is your tuning for the string at the bottom.